The main scientific work takes place in the phenotype-specific working groups, which have responsibility for developing and executing the scientific plans. Working groups standardize phenotypes across the cohorts, decide whether and how to include other non-member studies with similar phenotypes, and agree on analysis plans, often with input from the Analysis Committee. The phenotype working groups also develop plans for authorship and manuscripts, evaluate results, write manuscripts, and decide on the need for follow-up genotyping.
