and Use Committees of Emory University and Wake Forest School of Medicine. Monkeys were killed for analysis and necropsied on average at age 6.2 years (range between 3.6 and 8.2 years old) after the six-month treatment protocol by an overdose of barbiturate and transcardially perfused with ice cold saline. The brains were removed and cut into 4-mm slabs in the coronal plane using a brain matrix (EMS, Fort Washington, PA) and immediately frozen and stored at −80 °C.Table 2Summary of key variables from Rhesus macaques drug response experiments.TreatmentNumber AnimalsSex - F/MClozapine95/4Haloperidol-high74/3Haloperidol-low105/5Placebo84/4
