The GWAS Catalog (www.ebi.ac.uk/gwas; 6) is a publicly available, manually curated resource of all published GWAS and association results, collaboratively produced and developed by the NHGRI and EMBL-EBI. It includes all eligible GWAS studies since the first published GWAS on age-related macular degeneration in 2005 (7). As of 1st September 2016 it contains 24,218 unique SNP-trait associations from 2,518 publications in 337 different journals. The Catalog summarizes a large body of diverse and unstructured data from the literature in an accessible, expertly curated and quality controlled resource. Catalog data are used by biologists, bioinformaticians and clinical/translational researchers as a starting point for further investigations to identify causal variants, understand disease mechanisms, and establish targets for novel therapies. Examples of such work include the analysis of Catalog data for identification of other traits associated with type 1 diabetes loci by Onengut-Gumuscu et al. (8); for evidence of pleiotropy by Sivakumaran et al. (9); for loci associated with seven common diseases to identify possible causal missense variants by Pal and Moult, 2015 (10); and for identification of new targets for known drugs
