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Chunk #8 — Methods

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Butyrylcholinesterase genetic variants: association with cocaine dependence and related phenotypes.
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To conduct a comparative analysis according to the route of cocaine administration, we divided the patient sample into three subgroups: those who reported using only powder cocaine (typically by snorting); those who reported using only freebase cocaine hydrochloride (crack cocaine) which is smoked in small pipes and, those who reported using both routes of cocaine administration (dual users). A detailed description of the above subgroups can be found elsewhere [13].