In summary, findings suggest that CBT produces large treatment effects for treatment efficacy, treatment response, and symptom/diagnostic remission. The presence of greater comorbid anxiety disorders and TS/CTD, greater therapeutic contact, and decreased treatment attrition were found to be associated with greater CBT treatment effects. Meanwhile, SRIs produce moderate treatment effects for treatment efficacy, treatment response, and symptom/diagnostic remission. Although methodological quality was associated with smaller treatment effects, no other characteristics influenced treatment effects across trials. Although we encourage the future examination of patient-level moderator analyses from these combined RCTs, in their absence, these findings provide some guidance to practicing clinicians. From a clinical perspective, these findings provide three practical implications. First, these findings provide clinicians with probabilistic treatment response and symptom/diagnostic remission rates in response to empirically-supported monotherapies, which can be useful to inform families in the treatment selection process and aid patient/parent expectations. Second, these findings suggest that youth with either comorbid anxiety disorders or TS/CTD are good candidates for CBT. Third, these findings indicate that improved CBT therapeutic outcomes were associated with greater therapeutic contact and lower attrition
