MOFAM is a high risk alcoholism family study oversampled for AA families. From 2003 to 2009, Missouri state birth records were used to identify families with at least one child aged 13, 15, 17 or 19 years (the same age range targeted in MOAFTS) and 1 or 2 additional full siblings. Biological mothers completed brief telephone screening interviews to determine familial risk level for alcoholism. Families where biological fathers had a history of excessive drinking were classified as “high risk.” All others were classified as “low risk.” An additional group of families was selected from men identified as having 2 or more drunk-driving convictions (“very high risk”). In all participating families, mothers were interviewed first. Biological fathers were then solicited for interview and permission was sought from mothers to recruit offspring. Three hundred seventeen families of non-AA (primarily EA) descent and 450 AA families (92% of targeted families) were enrolled in the study. Sample enrollment occurred over 6 years. Three of the intake years had 4 waves of data, collected at two-year intervals; the remainder had 1 to 2 waves.
