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Chunk #21 — Results

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Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
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Figure 2 demonstrates that individuals with CC genotype for the rs1361995 SNP show significantly lower theta ERO power compared with those with CT or TT genotypes. Similar difference in the electrophysiological quantitative phenotypic variables in relation to different genotypes was also observed in the rs10487457 and rs10487459 SNPs. The same genotypes in these 3 SNPs that are associated with the reduction in the theta ERO power are also found to be associated with increased vulnerability to develop alcohol dependence (Table 3).