varenicline and combination NRT produced estimated abstinence rates of 33 and 37%, respectively3, rates that were significantly higher than a representative monotherapy such as the nicotine patch. Because both combination NRT and varenicline produce higher abstinence rates than other pharmacotherapies3,37, clinicians should encourage their use. Importantly, cessation medications are effective in clinical use in real world healthcare settings and with a wide variety of smokers (e.g., in those with substance abuse and depression diagnoses)3,19.
