with case–control comparisons made using the same set of 2938 controls).15 When we apply our analytic approach to our set of people with ‘schizophrenia spectrum’ (i.e. schizophrenia and schizoaffective disorders – the latter set includes the 279 individuals from the bipolar disorder sample) we similarly observe that RDC schizoaffective disorder, bipolar type stands out in having more hits (RDC diagnoses: schizoaffective disorder, bipolar type (n = 299), hits 7, P = 0.023; schizoaffective disorder, depressed type (n = 114), hits 2, P = 0.81; schizophrenia (n = 257), hits 3, P = 0.53). Thus, within our data, and at the significance threshold considered, the participants with RDC schizoaffective disorder, bipolar type stand out from both the other participants with bipolar disorder and the schizophrenia groups.
