in the maze, including erroneous turns (Figure 4A). In situations when keeping track of two concurrent information streams (local and distant cues) were required for correct behavioral performance, two distinct assemblies toggled between representations of the two spatial frames (Johnson et al., 2009; Kelemen and Fenton, 2010). In accordance with experiments in rodents, single unit studies in human patients showed that the hippocampus and entorhinal cortex can generate numerous trajectories corresponding to different memory episodes, and, importantly, that the neurons which fire during free recall are part of the same cell assembly sequences that were activated while watching the cinematic episodes in the learning phase (Gelbard-Sagiv et al., 2008).
