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Chunk #7 — Results — PrediXcan method

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A gene-based association method for mapping traits using reference transcriptome data.
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We use reference transcriptome datasets from studies such as GTEx13, GEUVADIS15, and DGN16 among others, to train additive models of gene expression levels. These models allow us to estimate the genetically regulated expression, GReX. We denote the estimated value with a hat, GReX^ These estimates constitute multiple-SNP prediction of expression levels. The weights for the estimation are stored in our publicly available database.