Chunk #9 — Methods and Materials — Phenotypes — Pack Years (PckYr).

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Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.

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Defined in the same way as cigarettes per day but not necessarily binned, divided by 20 (cigarettes in a pack), and multiplied by number of years smoking. This yielded a measure of total overall exposure to tobacco and is relevant to disease outcomes for which smoking is a risk factor, such as cancer and chronic obstructive pulmonary disease risk.