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Chunk #25 — Results — Results of best-fit model

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Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence.
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The parameter estimates for model 19 are depicted in Figure 1. Focusing first on the three genetic common factors, factor 1 had the highest loadings for the probe questions about quantity and frequency of alcohol consumption, and on the tolerance criterion. We therefore called this factor: tolerance/excess drinking. The second genetic factor loaded most strongly on the probe questions reflecting perception of having an alcohol problem and on the criteria for loss of control, desire to quit, preoccupation and activities given up. We called this factor: loss of control/social dysfunction. The highest loadings on the third genetic factor were for the withdrawal and continued use despite problems criteria. We labeled this factor: withdrawal/continued use.