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Chunk #17 — DISCUSSION

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Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium.
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None of the 23 SNPs in MACROD2 with p<10−5 was significantly associated with gene expression in publicly available genome-wide expression quantitative trait loci (eQTL) datasets (Appendix, Section 6), but this finding should be interpreted cautiously as less than half of these SNPs were present on any of the genotyping arrays used in these studies and eQTL may be tissue and insult specific.