The data used in this analysis came from Waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), designed by the National Institute on Alcohol Abuse and Alcoholism. The 2001-2002 Wave 1 NESARC sample represented U.S. adults 18 years or older residing in households and noninstitutional group quarters in all 50 states and the District of Columbia (n = 43,093, response rate = 81.0%). In Wave 2, the reinterview rate among eligibles (those who had not died, become incapacitated or institutionalized or left the country and were not in the military for the duration of the Wave 2 interviewing) was 86.7%, yielding a Wave 2 sample of 34,653 adults and a cumulative response rate of 70.2%. Wave 2 data were weighted to reflect design characteristics, including oversampling of Blacks, Hispanics and young adults, and nonresponse relative to sociodemographic characteristics and Wave 1 lifetime substance use and other psychiatric disorders. Weighted data were then adjusted to match the civilian, noninstitutionalized population of the United States on socioeconomic variables based on the 2000 Decennial Census. Data were