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Chunk #18 — Discussion

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Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks.
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statistically significant evidence for formal replication for the SNP in SLC35G1 and stronger evidence for association at many of the top SNPs after including the replication samples. Finally, these cohorts have higher rates of polysubstance dependence than the general population and may not be generalizable to individuals who only use cannabis.