Chunk #59 — FINDINGS — Relation of Risk Factors to Neuropathologic Indices (Table 3)

Source

Overview and findings from the rush Memory and Aging Project.

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The APOE ε4 allele was associated with greater AD pathology and the ε2 allele was associated with less AD pathology [165]. Similar findings were seen with CR1 and CEPT suggesting that these polymorphisms are also associated with AD in part through an association with AD pathology [83,141]. A number of other polymorphisms were related to AD pathology in a candidate gene study [166–168].