Chunk #37 — Methods — Mortality and disease burden attributable to individual and clusters of risk factors

Source

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

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Where r is each individual risk factor, and R is the number of risk factors. This approach assumes that risk factors are independent—ie, it does not account for mediation, exposure correlation, or effect size modification that might exist between risk factors in a cluster.155