Enrichr currently contains 102 gene set libraries belonging to eight categories. In total, there are currently 180 184 annotated gene sets within Enrichr. So far, 1 050 236 gene sets have been uploaded for analysis with Enrichr. While most (∼65%) users submit only 1–3 lists to Enrichr, there are also many heavy users where the distribution of lists submitted per user fits a well-behaved power law (Figure 2A). The submitted lists' size also follows a power-law distribution, but contains a peak around ∼250 genes per list (Figure 2B). This peak is likely an artifact from submissions that arrive from the tool GEO2Enrichr, which has a default setting of posting the top 500 genes separated into up-regulated or down-regulated genes from signatures processed from GEO. Examining the occurrence of individual genes in a submitted gene sets, we observe a log-normal distribution (Figure 2C) with the most popular genes: EGR1, FOS, TXNIP, DDIT4 and SGK1. EGR1 and FOS are well-known immediate early genes (IEG), and their high presence likely confirms that these genes are most commonly found as differentially expressed. The appearance
