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Chunk #32 — DISCUSSION — Neuropeptides

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Gene Expression Changes in Glutamate and GABA-A Receptors, Neuropeptides, Ion Channels, and Cholesterol Synthesis in the Periaqueductal Gray Following Binge-Like Alcohol Drinking by Adolescent Alcohol-Preferring (P) Rats.
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Overall, the results with the neuropeptides suggest that repeated binge-like alcohol drinking in these adolescent rats resulted in alterations in the expression of genes within the PAG that could increase anxiety and reactivity to stress.