for detecting reversal of global alcoholism-related brain damage that remains understudied is cerebral perfusion. The few studies examining perfusion improvements using arterial spin labeling MRI have yielded conflicting results. Mon et al. (2009) reported improvement of frontal and parietal gray matter perfusion after five weeks of abstinence, but Durazzo et al. (2010) were unable to detect longitudinal perfusion increases in parietal gray matter after an average of 35 days of abstinence. Thus, findings associated with recovery of overall brain integrity have been inconsistent.
