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Chunk #21 — 2. Experimental procedures — Imaging preprocessing and movement attenuation

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Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorder.
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All functional images were preprocessed in the same manner to reduce artifacts (Miezin et al., 2000). These steps included: (i) removal of a central spike caused by MR signal offset, (ii) correction of odd vs. even slice intensity differences attributable to interleaved acquisition without gaps, (iii) correction for head movement within and across runs, and (iv) within-run intensity normalization to a whole brain mode value of 1,000. Atlas transformation of the functional data was computed for each individual via the MPRAGE scan. Each run was then resampled in atlas space (Talairach and Tournoux, 1988), combining movement correction and atlas transformation in one interpolation. All subsequent operations were performed on the atlas-transformed volumetric time series.