the KCNJ6 SNPs, as increased theta activity during cognitive tasks is indicative of efficient processing (Klimesch, 1999; Basar et al., 2001b). On the other hand, lack of frontalization in theta EROs observed in those carrying minor alleles may be suggestive of delayed brain maturation in these individuals. Future studies are needed to determine the specific effects of KCNJ6 on cognitive (dys)functions. Further, since KCNJ6 / GIRK2 has been shown to be linked with the brain reward system though its modulation of dopaminergic signaling (Arora et al., 2010; Luscher and Slesinger, 2010; Cooper et al., 2012; Kotecki, 2015), these genetic findings with reward related brain oscillations may have behavioral and clinical implications.
