The GERA GWAS discovery stage did not indicate significant genomic inflation with genomic-control (λ)26 values of 1.063, 1.058, and 1.065 for SBP, DBP, and PP, respectively (Supplementary Figures 1-4, Online Methods). In addition to the linear regression analytic approach used in previous GWAS13,14,17 we used a mixed model approach that yielded slightly smaller λ values, suggesting an improved population substructure and/or cryptic relatedness adjustment (Supplementary Table 2). We detected 75 independent, genome-wide significant (P≤5×10−8) loci associated with one or more BP phenotypes (Supplementary Figures 1-4, Supplementary Tables 1-5).
