Additional file 1 : Supplementary Fig. 1. Regulation of Bdnf exon mRNA expression in the mPFC by chronic unpredictable stress. a Gene structure of the mouse Bdnf gene. bBdnf exon-specific mRNA expression levels in control and CUS groups. *p < 0.05, **p < 0.01 compared with control group. Additional file 2 : Supplementary Fig. 2. Selective deletion of Bdnf in the mPFC cannot induce depression-related behaviors in virgin female mice. a Schematic of the experimental timeline. b Sucrose preference test. c Forced swimming test. d Novelty-suppressed food test.