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Chunk #15 — Methods — Individual difference measures

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Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes.
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The Marijuana Dependence Checklist (MDC) is based on DSM-IV criteria and consists of the following: (i) wanted or tried to cut down on cannabis use but could not; (ii) the same amount of cannabis had less effect or the same effect took more; (iii) spent a great deal of time getting, using or getting over the effects of cannabis; (iv) used cannabis more often or in larger amounts than wanted to; (v) kept from engaging in work, school or recreation; (vi) cannabis-related psychological problems; and (vii) cannabis-related health problems. The sum of the symptoms endorsed is a proxy measure of the extent of marihuana use disorder (abuse and dependence symptoms).