Of 2656 VACS-BC participants (1721 HIV+; 935 uninfected) with PEth data (1529 HIV+; 836 uninfected), a total of 2344 participants (1513 HIV+ and 831 uninfected) also had complete AUDIT-C data and were included in the final sample of this study. The median age at blood draw was 52 and 53 years among HIV+ and uninfected individuals, respectively. Over half the sample were aged 50 to 64 years, 95% were men, 70% had at least some college education, 36% had hepatitis C infection, 27% were current smokers, and 9% reported using IV drugs in the past year (Table 1). Approximately two-thirds of the 1513 HIV+ participants had suppressed viral load (≤ 500 copies/mL) at blood collection date. Characteristics of the restricted sample were very similar to those of the full sample. The median time between blood draw (PEth measurement) and AUDIT-C survey date was 46 days (25th, 75th percentile: 0, 222) for the entire sample (n= 2344). For the restricted sample (n=682), the median time between dates was 0 days (25th, 75th percentile: 0, 0), and 91% had a blood draw and AUDIT-C survey on the same day.