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Chunk #7 — SUMMARY STATISTICS IN THE GWAS CATALOG

Source
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019.
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Full P-value summary statistics have been available for selected studies from project specific websites for some time, for example, the Psychiatric Genetics Consortium has offered downloads for published studies since 2013 (https://www.med.unc.edu/pgc/results-and-downloads). More recently, funders such as NIH have assessed the risks associated with sharing aggregate genomic information and this has driven current community practice of sharing aggregate SS for GWAS in a project-centric model. This presents challenges for users who must first find, then harmonize, organize and manage the data related to individual studies from multiple sources. This prompted the Catalog to respond to changing community practice and the Catalog now accepts submissions of SS in support of eligible GWAS Catalog papers and has developed new infrastructure to support user access to these data.