(p<10−4) deviation from Hardy Weinberg equilibrium were observed. Additional details are provided in Edenberg et al. (2010). The GWAS analysis was conducted in PLINK version 1.05, for all autosomes and the X chromosome, with age and sex included as covariates. An additive model was assumed, and because of the binary outcome variable, logistic regression was used. Annotations are based on assembly GRCh37/hg19. Gene names were assigned to markers based on RefSeq gene sequences.
