East Asian GWAS find the same risk allele and similar log(OR) than European discovery GWAS. X axis: log(OR) for the replication stage of the discovery European GWAS. Y axis: log(OR) for the initial stage of East Asian GWAS (Materials and Methods). Dots in blue indicate significant (P<0.05) replication attempts in East Asia; dots in grey indicate non-significant replication attempts. (A) Using all replication attempts; (B) Using only the most-powered replication attempt per SNP; (C) Using the most-powered replication attempt per region. Attempts correspondent to SNPs with MAF<0.01 in East Asians are not shown.
