Structural equation models in Mplus v8.5 were employed to examine the main effects of nine COVID-19-related stress and healthy coping latent factors (initially estimated in independent models) on change in drunkenness frequency. Stratified analyses were conducted for those without a prior history of AUD (0) and three groups of participants with a lifetime history of AUD, including (1) those who were experiencing AUD symptoms pre-pandemic, (2) those who were in remission from AUD and drinking, and (3) those in remission and had not consumed alcohol at all for 1+ years. Further, gender-stratified models were examined. Exploratory models examined multiplicative interactions between COVID-19-related stress and coping latent factors with problematic alcohol use PRS (z-score standardized) and low alpha EEG interhemispheric coherence (z-score standardized).