alcoholics were decreased by 1.46-fold (Table 2) but the differences did not reach statistical significance. The levels of p65 in the MC, and those of p50 and IKKβ proteins in neither the PFC (Table 2; n = 15) nor MC (Table S2; n = 15) differed significantly between control subjects and alcoholics. We were unable to analyze other NF-κB related proteins including cREL, IκBα, IKKα and IKKγ in postmortem human brain samples due to the absence of specific and sensitive antibodies suitable for such study or low levels of expression.
