Comparison of the present findings with P rats injected with ethanol (Table 2) and proteomics studies with autopsied alcoholic brains (Matsuda-Matsumoto et al., 2007; Alexander-Kaufman et al., 2006, 2007; Lewohl et al., 2004) indicated few proteins or classes of proteins in common between the P rats and human studies. In the present study (Table 2) and the results of Matsuda-Matsumoto et al., (2007) for the hippocampus, only guanine nucleotide-binding (Gn) proteins were altered by ethanol treatment in both the present study and the post mortem study.
