The 66 men included in this report were primarily White (including White Hispanic) (65.2%), with an additional 28.8% Black and 6.1% other racial backgrounds. At the time of alcohol challenges the group had an average age of 22.2 years (standard deviation 3.93), they weighed 80.5 (12.42) kilograms, and their Subjective High Assessment Score (SHAS) focusing on the seven most informative items at 60 minutes was 66.1 (58.52). All subjects had a first- or second-degree relative with an AUD. The average quantity of drinking per drinking day as determined from questions extracted from the SSAGA was 2.8 (2.80) at T1 alcohol challenge, with a quantity of 3.4 (2.73) at follow-up (t = 1.56, p = .12 across the measures). The time between alcohol challenge and SRE was 0.91 (1.41) years, the period between alcohol challenge and follow-up was 4.9 (1.71) years, while time between SRE and follow-up was 3.9 (1.77) years. Regarding potential non-independence, for 85.2% of families only one offspring had been included per family, 9.3% had two, and 5.6% three or four.