0.34.45 In light of the relatively modest additive heritability for SLC1A1 expression now determined in our analysis, it is not surprising that the eQTL markers identified herein also had a small effect size (Figure 1). Nevertheless, our approach proved valuable, not only because it identified a previously OCD-associated SNP, rs301430, as an eQTL, but also because (1) the 3-marker haplotype that was strongly associated with OCD contained 2 eQTLs, and (2) another eQTL marker farther upstream correlated with an OCD hoarding subphenotype.
