Chunk #2 — Introduction

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The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.

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(Ferreira et al., 2008; Rueckert et al., 2012; Smith et al., 2009). ANK3 has also been associated with schizophrenia, anhedonia, behavioral activation, and novelty-seeking (Athanasiu et al., 2010; Ripke et al., 2011; Roussos et al., 2011; Roussos et al., 2012), suggesting a broader role in psychiatric illness and traits.