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Chunk #33 — Discussion

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Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
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EA. Findings from this study, together with the previous literature on genetic correlations between other psychiatric disorders and problematic v. typical alcohol use, consistently indicate that problematic alcohol use and more typical alcohol use are genetically associated with other psychiatric disorders in opposite directions. These findings suggest that alcohol-related behaviors are heterogenous, and specifically that the genetic associations between consumption and alcohol-related problems and PTSD differ in strength and direction.