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Chunk #39 — Discussion

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Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
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In summary, we report 81 loci associated with PTSD in EA meta-analysis and 85 loci when expanding to cross-ancestry analyses. While these results represent a milestone in PTSD genetics and point to exciting potential target genes, further investment into data collection from underrepresented populations of diverse ancestries is needed for identification of additional risk variants and to generate equitable and more robust PRS.