A relatively novel subject of genetic enquiry, there have been only 10 candidate gene studies of disordered gambling.72 Two correlated variants in the gene encoding the dopamine receptor 1 (DRD1) have been reported to be associated with disordered gambling—rs4532 (-48G>A or -48DdeI)73 and rs265981 (5262T>C, -800HaeIII).74 However, a recent study by Lobo et al.75 did not replicate this association.
