We calculated burden attributable to all (67) risk factors and clusters of risk factors except for physiological risks and air pollution. These two clusters present analytical challenges for computation of the aggregate burden. For example, the effects of high body-mass index are partly mediated through high blood pressure, high total cholesterol, and high fasting plasma glucose, and household air pollution from solid fuels (wood, crop, residues, animal dung, charcoal, and coal) contributes to ambient particulate matter pollution.
