(21%) of the ASD families with IQ ≥ 70 were from AGRE. The exact number of overlapping families between our AGRE data and those in the two previous studies is unknown. To test if our linkage results were independent confirmation of the previous reported linkage signals, we repeated the linkage analysis without any of the AGRE families. The linkage signals remained at both loci with the LOD scores changed from 3.40 to 2.78 (p = .0002) for the locus on chromosome 11 using the ASD families with DelayedPhrase and from 4.01 to 2.59 (p = .0003) for the locus on chromosome 15 using the ASD families with IQ ≥ 70.
