The FA of callosal fibers significantly correlated with age in the superior frontal segment (r = −0.604, p = 0.006) and posterior parietal segment (r = 0.506, p = 0.027) in the HC group and in the anterior frontal segment (r = −0.481, p = 0.037) in the SZ group. There were no significant correlations between the FA of callosal fibers and equivalent dose of antipsychotics in the SZ group.