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Chunk #36 — Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery

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Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits.
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genes associated with the physiological response to psychological stress, particularly in the HPA axis, are natural candidates for G×E research on stress and depression (132). Genes regulated by hypoxia are candidates for G×E research on obstetric complications and schizophrenia (133). Genes involved in biosynthesis of fatty acids are candidates for G×E research on nutrition and brain development (134). Genes involved in lead absorption are relevant for research on attention deficits and hyperactivity (135). Genes involved in ototoxicity are relevant for research on learning difficulties (136).