Chunk #14 — eQTL analysis of breast cancer risk loci — Cis- analysis

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Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.

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We focused on 15 breast cancer loci previously reported by genome-wide association studies (P < 5×10-8, Table S4, related to Table 1)(Hindorff LA). We identified three significant cis-associations mapping to risk loci at 2q35 (IGFBP5), 5q11 (C5orf35) and 16q12 (TOX3)(FDR<0.1, Table S5).