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Chunk #9 — Materials and methods — Phenotype and covariates

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Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.
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For all individuals, the data were available on whether or not the subject reported having ever used cannabis during their lifetime: yes (1) versus no (0). Although phrasing of the question slightly differed between samples (see Supplementary Information 1), our unit of analysis reflected lifetime cannabis use in all the samples.