Chunk #58 — Aldehyde dehydrogenase enzymes — ALDH2

Source

Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review.

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Text

In Japan, the protection against AD from a single ALDH2*2 allele dropped sharply from 1979 to 1992, as the pressure to drink socially and as part of business culture increased (Higuchi et al., 1994). This is a striking example of gene x environment interaction.