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Chunk #12 — Methods — Statistical methods

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Tobacco smoking and all-cause mortality in a large Australian cohort study: findings from a mature epidemic with current low smoking prevalence.
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Among current and never-smokers at recruitment, mortality rates and RRs by amount smoked were calculated according to categories of consumption reported at recruitment (≤14, 15–24, and ≥25 cigarettes/day). Mortality rates were then plotted against the mean number of cigarettes within each category reported at the 3-year resurvey among those who reported being current smokers at resurvey, as this was considered the best estimate of long-term mean consumption among all in that category, before the study started (Additional file 1: Table S1). Rates in never-smokers were plotted against the “0” on the x-axis. The RR of dying during the follow-up period was then quantified among past versus never-smokers, in those ceasing smoking at ages <25, 25–34, 35–44, and 45–54 years. Sensitivity analyses were conducted restricting the data to individuals aged ≥55 years, ensuring that all participants had the opportunity to quit at these ages.