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Chunk #26 — DISCUSSION — Limitations

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Anorexia Nervosa, Major Depression, and Suicide Attempts: Shared Genetic Factors.
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The results of this study should be evaluated within the context of the limitations. First, the data used came from adult women from Sweden; results might not be generalizable to men or to different ancestry and age groups. Second, STAGE data were collected via computer-administered assessments. Although computer-administered self-report assessments might be less precise than interview-based assessment methods, participants might be more forthcoming with sensitive information (Lind et al., 2013). Third, SA were only captured if the result of the attempt required clinical care. Thus, results may only apply to more serious attempts. Fourth, causal conclusions regarding which specific genetic and/or unique environmental factors that may be involved in the associations between the three disorders cannot be determined. Fifth, there is likely some confounding between MDD and both AN and SA since the symptom list for MDD includes appetite, weight changes, and suicidal ideation.