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Chunk #27 — Results — Genetic association and heterogeneity analyses

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In search of causal variants: refining disease association signals using cross-population contrasts.
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There are additional SNPs correlated with rs16969968 according to the current HapMap CEU build that were not genotyped and analyzed in our samples; one of these additional SNPs (rs7180002) was in fact attempted by CIDR but removed during quality control due to poor clustering (more than 3 genotype clusters). However, it is useful to note that according to HapMap YRI, rs7180002 is in perfect LD (r2 = 1) with the genotyped rs951266 (Figure 2) and therefore is very likely to have association and heterogeneity results very similar to those of rs951266. For the other non-genotyped SNPs, the YRI LD patterns do not indicate strong correlations with our genotyped SNPs, and we therefore cannot draw conclusions for these.