In summary, this traditional between-group approach does provide extensive, valuable information about potential ADHD pathophysiology related to the NAcc. However, this approach and its findings also have some inherent limitations. First, since ADHD is a heterogeneous disorder, it is likely that not all the children in the ADHD group present the alterations found here. Second, and most important, we do not know how any given difference relates to specific behavioral components that accompany the ADHD phenotype.
